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Diabetes > Aldose Reductase
The following information is about Aldose Reductase.
Aldose Reductase Defined
An enzyme that is normally present in the eye and in many other parts of the body. It changes glucose (sugar) into a sugar alcohol called sorbitol. Too much sorbitol trapped in eye and nerve cells seems to damage these cells, and may be part of the cause of diabetic retinopathy and neuropathy. There are medications that interfere with aldose reductase.
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Tue Nov 25
- Sorbitol - Wikipedia, the free encyclopedia: This will aid in the understanding of how accumulation of glucose can lead to cellular damage; the aldose reductase converts glucose to sorbitol, a sugar alcohol that can lead to problems such as glaucoma.
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