One of several different classes of pills that lower the level of glucose in the blood. Used in Type 2 diabetes.There are several sulfonylurea pills available. Four, known as "first-generation" drugs, have been in use for some time. Three types, called "second-generation" drugs, have been developed recently. They are sometimes stronger than first-generation drugs and have fewer side effects. Each type of pill is sold under two names: one is the generic name as listed by the US Food and Drug Administration; the other is the trade name given by the manufacturer. They are:First-Generation Agents:Generic Name: TolbutamideTrade Name: OrinaseGeneric Name: AcetohexamideTrade Name: DymelorGeneric Name: TolazamideTrade Name: TolinaseGeneric Name: ChloropropamideTrade Name: DiabineseSecond-Generation Agents:Generic Name: GlipizideTrade Name: Glucotrol, Glucotrol XLGeneric Name: GlyburideTrade Name: Diabeta, Micronase, GlynaseGeneric Name: GlimepirideTrade Name: AmarylSee also: Oral hypoglycemic agents.

This definition is in context to Diabetes. See more contextual defintions for Sulfonylureas.