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Diabetes > Thiazolidinediones
The following information is about Thiazolidinediones.
Thiazolidinediones Defined
One of several different classes of pills that lower the level of glucose in the blood. Used in Type 2 diabetes. There are several thiazolidinedione pills available. This class of medications is also called "glitazones."Each type of pill is sold under two names: one is the generic name as listed by the US Food and Drug Administration; the other is the trade name given by the manufacturer. The thiazolidinediones that are presently available are:Generic Name: rosiglitazoneTrade Name: AvandiaGeneric Name: pioglitazoneTrade Name: ActosSee also: Oral hypoglycemic agents.
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Off-site Thiazolidinediones Links, User Submitted
The following links have been collected through user bookmark submission in the Thiazolidinediones category. Please note, because these resources are off-site we cannot guarantee the accuracy or quality of any information.
Tue Jun 23
- Heart study questions diabetes drugs : Nature News | A molecular pathway could explain how a class of drugs leads to heart failure.: A class of diabetes drugs including Avandia is known to raise the risk of heart failure. Researchers who study how tumours balloon in size have discovered one way that enlargement of the heart can lead to heart failure. The work, although mostly done in mice, could help explain why a class of diabetes drugs called thiazolidinedi ones (TZDs) increase the risk of heart failure. A 2007 analysis of Avandia (rosiglitazone ), a TZD made by GlaxoSmithKlin e, suggested that patients taking it are at increased risk of heart attack. Less controversial are data linking TZDs with heart failure, a distinct condition in which the heart cannot pump enough blood through the body. "We already knew if you had heart failure you probably should not be taking these drugs, but this paper provides an additional explanation why," says Clay Semenkovich, an endocrinologis t. The work suggests that a molecule activated by TZDs, called PPAR-?, underlies one aspect of heart failure.
Wed Apr 8
- Diabetes medication pills information: Alpha-Glucosid ase Inhibitor, Biguanide, D-Phenylalanin e derivative, DPP-4 Inhibitor, Meglitinide, Sulfonylurea, Thiazolidinedi one & its side effects.
Tue Jan 13
Fri Nov 16
Wed Oct 3
- Thiazolidinedi ones: effects on insulin resistance and the cardiovascular system ____FREE PDF: C E Quinn, P K Hamilton, C J Lockhart and G E McVeigh. Br J Pharmacol advance online publication, October 1, 2007; doi:10.1038/sj .bjp.0707452
Sat Jul 14
- Lab disaster may lead to new cancer drug - Cancer - MSNBC.com: So you're telling me that thiazolidinedi ones (rosiglitazone , pioglitazone, etc.) can cure colon cancer? This should be easy to study: find all your diabetics and see if they have a lower rate of colon cancer than the general population. GSK? Takeda Pharma
Mon Dec 4
Tue Nov 28
Sat Feb 5
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